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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pediatricjournal</journal-id><journal-title-group><journal-title xml:lang="ru">Архив педиатрии и детской хирургии</journal-title><trans-title-group xml:lang="en"><trans-title>Archives of Pediatrics and Pediatric Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2949-4664</issn><issn pub-type="epub">3033-6783</issn><publisher><publisher-name>НИКИ детства Минздрава Московской области</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pediatricjournal-153</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>АРТЕРИАЛЬНАЯ ГИПЕРТЕНЗИЯ, ОЖИРЕНИЕ  И ПОРАЖЕНИЕ ОРГАНОВ-МИШЕНЕЙ У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5533-0205</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белых</surname><given-names>Наталья Анатольевна</given-names></name></name-alternatives><email xlink:type="simple">nbelyh68@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБОУ ВО РязГМУ Минздрава России</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>05</day><month>06</month><year>2026</year></pub-date><volume>3</volume><issue>3</issue><elocation-id>153</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Белых Н.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Белых Н.А.</copyright-holder><copyright-holder xml:lang="en">Белых Н.А.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nikid.ru/jour/article/view/153">https://journal.nikid.ru/jour/article/view/153</self-uri><abstract><sec><title>Цель</title><p>Цель: изучить данные о связи между детским ожирением и артериальной гипертензией, их влиянии на поражение органов-мишеней и современные возможности терапии.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В ходе исследования были проанализированы публикации, размещенные в российских и зарубежных базах данных (eLibrary, PubMed, Google Scholar, UpToDate) преимущественно за последние 5 лет по следующим ключевым словам: «артериальная гипертензия», «детское ожирение», «поражение органов-мишеней», «hypertension», «childhood obesity», «target organ injury». При анализе данных учитывали все публикации, посвященные сочетанию детского ожирения и артериальной гипертензией, их влиянию на поражение органов-мишеней, методах диагностики и лечении.</p></sec><sec><title>Результаты</title><p>Результаты. Распространённость артериальной гипертензии и ожирения в детской популяции растёт, несмотря на усилия общественного здравоохранения. Артериальная гипертензия и ожирение способствуют выработке провоспалительных цитокинов, которые активируют ренин-ангиотензин-альдостероновую систему и симпатическую нервную систему, что приводит к негативным последствиям в регуляции АД и функции почек. При повышенном АД могут наблюдаться неблагоприятные изменения в работе сердца, сосудов, почек, сетчатки глаза и нарушаться нейрокогнитивные функции. Результаты последних исследований свидетельствуют о достижениях в области терапии артериальной гипертензии и ожирения у детей, что способно снизить риск повреждения органов-мишеней в педиатрической популяции.</p></sec><sec><title>Выводы</title><p>Выводы. Артериальная гипертензия и ожирение оказывают значительное влияние на ПОМ у детей. Мероприятия по нормализации АД и терапии детского ожирения способны уменьшить гипертрофию левого желудочка, улучшить показатели систолической и диастолической функции, а также функцию почек. Надлежащий скрининг и лечение этих заболеваний могут снизить потенциальное негативное влияние на сердечно-сосудистую систему в будущем.</p></sec></abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>детское ожирение</kwd><kwd>поражение органов-мишеней</kwd><kwd>гипертрофия миокарда левого желудочка</kwd><kwd>скорость пульсовой волны</kwd><kwd>толщина интимы-медии сонной артерии.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kontis V, Cobb LK, Mathers CD, Frieden TR et al. Three Public Health Interventions Could Save 94 Million Lives in 25 Years. 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