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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pediatricjournal</journal-id><journal-title-group><journal-title xml:lang="ru">Архив педиатрии и детской хирургии</journal-title><trans-title-group xml:lang="en"><trans-title>Archives of Pediatrics and Pediatric Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2949-4664</issn><issn pub-type="epub">3033-6783</issn><publisher><publisher-name>НИКИ детства Минздрава Московской области</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/2949-4664-apps-2-1-182-195</article-id><article-id custom-type="elpub" pub-id-type="custom">pediatricjournal-72</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Стресс в детском возрасте: клинические последствия и терапевтические стратегии</article-title><trans-title-group xml:lang="en"><trans-title>Stress in childhood: clinical implications and therapeutic strategies</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3606-4068</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шрайнер</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shreiner</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балакирева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Balakireva</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3522-5384</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Быстрова</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Bystrova</surname><given-names>V. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7041-5071</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ковалева</surname><given-names>А. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovaleva</surname><given-names>A. Ya.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7308-7280</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хавкин</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khavkin</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">khavkin@nikid.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Новосибирский государственный университет; Институт химической биологии и фундаментальной медицины СО РАН<country>Россия</country></aff><aff xml:lang="en">Novosibirsk State University; Institute of chemical, Institute of Chemical Biology and Fundamental Medicine of the SB RAS<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Белгородский государственный исследовательский университет<country>Россия</country></aff><aff xml:lang="en">Belgorod State Research University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Новосибирский государственный университет<country>Россия</country></aff><aff xml:lang="en">Novosibirsk State University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">Институт химической биологии и фундаментальной медицины СО РАН<country>Россия</country></aff><aff xml:lang="en">Institute of chemical, Institute of Chemical Biology and Fundamental Medicine of the SB RAS<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru">Белгородский государственный исследовательский университет; Научно-исследовательский клинический институт детства Министерства здравоохранения Московской области<country>Россия</country></aff><aff xml:lang="en">Belgorod State Research University; Research Clinical Institute of Childhood, Ministry of Health of the Moscow Region<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>26</day><month>03</month><year>2024</year></pub-date><volume>2</volume><issue>1</issue><fpage>182</fpage><lpage>195</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шрайнер Е.В., Балакирева Е.А., Быстрова В.И., Ковалева А.Я., Хавкин А.И., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Шрайнер Е.В., Балакирева Е.А., Быстрова В.И., Ковалева А.Я., Хавкин А.И.</copyright-holder><copyright-holder xml:lang="en">Shreiner E.V., Balakireva E.A., Bystrova V.I., Kovaleva A.Y., Khavkin A.I.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nikid.ru/jour/article/view/72">https://journal.nikid.ru/jour/article/view/72</self-uri><abstract><p>Стресс - универсальный эволюционно детерминированный физиологический механизм, позволяющий в жизнеугрожающих ситуациях мобилизовать резервы организма. Однако, как любой мобилизационный процесс, он возможен только на коротком отрезке времени. Далее наступает истощение резервов и, согласно теории Ганса Селье, дистресс. В контексте организма человека, в нашем случае, организма ребёнка, дебютирует стрессиндуцированная патология, которая, нередко, носит системный характер, затрагивая многие органы и системы. Кроме того, стресс, выступая в роли эпигенетического фактора, может спровоцировать дебют заболеваний, к которым у конкретного индивидуума есть предрасположенность. В обзоре литературы представлена современная концепция стресса, его влияния на растущий организм ребёнка и описан ряд стрессассоциированных патологических состояний.</p></abstract><trans-abstract xml:lang="en"><p>Stress is a universal evolutionarily determined physiological mechanism that allows to mobilize of organism reserves in life-threatening situations. However, like any mobilisation process, it is possible only for a short period of time. Then, the reserves are depleted and, according to Hans Sellier’s theory, distress occurs. In the context of the human organism, in our case, the child’s organism, stress-induced pathology debuts, which often has a systemic character, affecting many organs and systems. In addition, stress, acting as an epigenetic factor, can provoke the debut of diseases to which a particular individual has a predisposition. The literature review presents the modern concept of stress, its influence on the growing organism of a child and describes a number of stress-associated pathological conditions.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>стресс</kwd><kwd>стрессиндуцированные заболевания</kwd><kwd>стратегии лечения и реабилитации</kwd></kwd-group><kwd-group xml:lang="en"><kwd>stress</kwd><kwd>stress-induced diseases</kwd><kwd>treatment and rehabilitation strategies</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Akarachkova E. S., Blinov D. V., Klimov L. V., Kotova O. V., Tsareva E. V. Stress and stress-associated disorders in children. Meditsinskiy sovet = Medical Council. 2023;(12):210-220. (In Russ.) doi: 10.21518/ms2022-016.@@ Акарачкова Е. С., Блинов Д. В., Климов Л. В., Котова О. В., Царева Е. В. Стресс и стресс-связанные расстройства у детей. 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