Using nailfold capillaroscopy to assess the effectiveness of ongoing therapy (dupilumab) in a patient with severe bronchial asthma
P. V. Berezhanskiy,
A. E. Khurgaeva,
A. B. Malakhov,
T. A. Gutyrchik,
S. I. Shatalina,
N. G. Kolosova https://doi.org/10.31146/2949-4664-apps-3-2-58-65
Abstract
Bronchial asthma remains a pressing public health issue due to its high prevalence, increasing incidence, and serious eco- nomic burden. Timely diagnosis, identifiation of predictors of the disease development, as well as assessment of treatment effectiveness are key factors for early detection, prevention of asthma progression, reduction of complication risk, and the development of personalized therapy, improving patients’ quality of life. We demonstrated the prospects and practical significance of using a microcirculation imaging method for disease diagnosis, as well as for assessing the effectiveness of biological therapy (dupilumab) in a patient with severe bronchial asthma.
About the Authors
P. V. Berezhanskiy
Clinical Research Institute for Childhood Diseases, Moscow Region Ministry of Health; Morozovskaya Children’s City Clinical Hospital; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University); Peoples’ Friendship University of Russia named after Patrice Lumumba
Russian Federation
Russian Federation
Pavel V. Berezhanskiy – Dr. Sci. (Med.), Senior Researcher, Department of Pediatrics; Pediatrician, Pulmonology department; Prof., Department of Pediatric Diseases, N.F. Filatov Clinical Institute of Child Health; Assoc. Prof., Department of Clinical Immunology, Allergology and Adaptology
24A, bldg. 1, Kominterna str., Mytishchi,141009
1/9, 4th Dobryninsky Lane, Moscow, 119049
19, bldg. 1, Bolshaya Pirogovskaya str., Moscow, 119991
6, Miklukho-Maklaya str., Moscow, 117189
A. E. Khurgaeva
Morozovskaya Children’s City Clinical Hospital
Russian Federation
Russian Federation
Anastasia E. Khurgaeva – Pediatrician
1/9, 4th Dobryninsky Lane, Moscow, 119049
A. B. Malakhov
Clinical Research Institute for Childhood Diseases, Moscow Region Ministry of Health; Morozovskaya Children’s City Clinical Hospital; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation
Russian Federation
Alexander B. Malakhov – Dr. Sci. (Med.), Head of Pediatrics Department; Pulmonologist, Department of pulmonology; Prof., Department of Pediatric Diseases, N.F. Filatov Clinical Institute of Child Health; Chief freelance pediatric pulmonologist, Moscow Department of Health and Moscow Region Ministry of Health
24A, bldg. 1, Kominterna str., Mytishchi,141009
1/9, 4th Dobryninsky Lane, Moscow, 119049
19, bldg. 1, Bolshaya Pirogovskaya str., Moscow, 119991
T. A. Gutyrchik
Morozovskaya Children’s City Clinical Hospital
Russian Federation
Russian Federation
Tatyana A. Gutyrchik – Pediatrician, Pulmonologist, Department of pulmonology
1/9, 4th Dobryninsky Lane, Moscow, 119049
S. I. Shatalina
Clinical Research Institute for Childhood Diseases, Moscow Region Ministry of Health; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation
Russian Federation
Svetlana I. Shatalina – Senior Researcher, Pediatrics Department; Cand. Sci. (Med.), Assist. Prof., Department of Pediatric Diseases, N.F. Filatov Clinical Institute of Child Health
24A, bldg. 1, Kominterna str., Mytishchi, 141009
19, bldg. 1, Bolshaya Pirogovskaya str., Moscow, 119991
N. G. Kolosova
I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation
Russian Federation
Natalia G. Kolosova – Cand. Sci. (Med.), Assoc. Prof., Department of Pediatric Diseases, N.F. Filatov Clinical Institute of Child Health
19, bldg. 1, Bolshaya Pirogovskaya str., Moscow, 119991
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For citations:
Berezhanskiy P.V., Khurgaeva A.E., Malakhov A.B., Gutyrchik T.A., Shatalina S.I., Kolosova N.G. Using nailfold capillaroscopy to assess the effectiveness of ongoing therapy (dupilumab) in a patient with severe bronchial asthma. Archives of Pediatrics and Pediatric Surgery. 2025;3(2):58-65. (In Russ.) https://doi.org/10.31146/2949-4664-apps-3-2-58-65
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